Diosmin

Short Description:

【Application】: Diosmin is a semi-synthetic flavonoid, a derivative of hesperidin. It is used to treat various vascular diseases, including hemorrhoids, varicose veins, poor blood circulation in the legs (venous stasis) and bleeding in the eyes or gums. It is also used to prevent liver toxicity. It is usually mixed with hesperidin.

【Specifications】: 90%-95%; 9:1

【Extraction source】: hesperidin which is extracted from dry young fruit of Rutaceae plant Lime and its cultivars or sweet orange, also known as "Fruit Citrus".

【Type】: Greyish-yellow or light yellow hygroscopic powder

【CAS No.】: 520-27-4

【Molecular Formula】: C28H32O15

【Molecular Weight】: 608.545

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Product Detail

Product Tags

Analysis	Specification	Method
Anhydrous substance	90.0-102.0%	HPLC
Hesperidin	≤4.0%	HPLC
Acetoisovanillone	≤0.5%	HPLC
Isorhoifin	≤3.0%	HPLC
Linarin	≤3.0%	HPLC
Diosmetin	≤2.0%	HPLC
Unspecified impurities, for each impurity	≤0.4%	HPLC
Total	≤8.5%	HPLC
Appearance	Greyish-yellow or light yellow hygroscopic powder.	Visual
Solubility	Practically insoluble in water, soluble in dimethyl sulphoxide, practically insoluble in ethanol (96%). It dissolves in dilute solutions of alkali hydroxides.	-
Odor & Taste	Characteristic	Organoleptic
Residual Solvents	Methanol≤3000ppm	CP2015
	Ethanol≤5000ppm
	Pyridine≤200ppm
Loss on drying	≤6.0%	CP2015
Sulphated ashes	≤0.2%	CP2015
Heavy Metals
Total	≤10ppm	CP2015
Microbiological Control
Total Plate Count	NMT1000cfu/g	CP2015
Yeast & Mold	NMT100cfu/g	CP2015
E.Coli	Negative	CP2015

Packing and Storage
Packing	25kgs/drum. Packing in paper-drums and two plastic-bags inside.
Storage	Store in a well-closed container away from moisture, sun light, or heat.
Shelf Life	2 years.